BDBM10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT
SMILES NCCc1c[nH]c2ccc(O)cc12
InChI Key InChIKey=QZAYGJVTTNCVMB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 46 hits for monomerid = 10755
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 1.10nMAssay Description:Ability to displace [3H]5-HT bound to 5-hydroxytryptamine 1B receptor in rat striatumMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 1.10nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptor of rat striatum.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1B receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 2.5nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 1B receptor from rat striatum using [3H]5-HT as radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(GUINEA PIG)
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]5-HT from 5-HT1B receptor of rat frontal cortex homogenateMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 4nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1D receptor beta in CHO cells transfected with human 5-HT1D beta gene labeled with [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 4nMAssay Description:Binding affinity of the compound towards cloned human 5-hydroxytryptamine 1D receptor beta was determined using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 4.80nMAssay Description:Ability to displace [3H]5-CT (1.5 nM) from HeLa cells of human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 1B receptor in CHO cells using [3H]5-CT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1B receptor was determined in male Sprague-Dawley rat brain.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 5.40nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 5.40nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1B receptor in rat striatum labeled with [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 6.80nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 6.80nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 7.10nMAssay Description:The compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 14nMAssay Description:Displacement of [125I]CYP from human 5HT1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataKi: 25nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Mus musculus (Mouse))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5HT1B receptor measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 4.60nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataEC50: 26nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 5nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataEC50: 30nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1A receptor of guinea pig hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataEC50: 4.82nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataEC50: 4.70nMAssay Description:The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5-HT1B receptor in the presence of isoproternolMore data for this Ligand-Target Pair